Teaching Video NeuroImages: Periodic alternating nystagmus evident only in darkness

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Teaching Video NeuroImages: periodic alternating nystagmus evident only in darkness.

An 81-year-old man with retinitis pigmentosa had severe, slowly progressive visual loss that began at age 20. Intermittent nystagmus was observed for 1 decade. Examination revealed severe retinal atrophy and periodic alternating nystagmus (PAN) that occurred only in darkness (video on the Neurology® Web site at www.neurology.org). PAN refers to horizontal nystagmus that periodically reverses di...

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Teaching video neuroimages: see-saw nystagmus.

A 43-year-old woman experienced a worsening of her usual headache. As a right hemifacial hypoesthesia had appeared, the patient underwent a brain MRI that revealed a giant cavernoma localized at the left meso-diencephalic region (figure, A and B). After the operation, an involuntary ocular oscillation known as see-saw nystagmus developed (video on the Neurology® Web site at www.neurology.org). ...

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Acquired Periodic Alternating Nystagmus

대한신경과학회지 22권 5호 548 Periodic alternating nystagmus (PAN) is a rare type of spontaneous horizontal nystagmus, characterized by periodical reverse of direction with a transition period in between. PAN can occur in both congenital and acquired forms. We report a patient with acquired PAN associated with meningoencephalitis. To our knowledge, only a case of congenital PAN has been previously report...

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Periodic alternating nystagmus in humans with albinism.

PURPOSE To quantify the spatial and temporal nature of congenital periodic alternating nystagmus (PAN) and to test the hypothesis that PAN results from a temporal shift in the null zone. METHODS Twenty-five subjects with oculocutaneous albinism (16 tyrosinase negative and 9 tyrosinase positive) and 7 with ocular albinism (5 x-linked and 2 autosomal recessive) participated in the study. Using ...

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Anti-GAD antibodies and periodic alternating nystagmus.

BACKGROUND Autoantibodies directed against glutamic acid decarboxylase (GAD-Ab) have recently been described in a few patients with progressive cerebellar ataxia, suggesting an autoimmune physiopathologic mechanism. OBJECTIVE To determine the exact role of GAD-Ab and gamma-aminobutyric acid (GABA)-ergic neurotransmission in the pathogenesis of cerebellar ataxia. DESIGN Case report. SETTIN...

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ژورنال

عنوان ژورنال: Neurology

سال: 2013

ISSN: 0028-3878,1526-632X

DOI: 10.1212/wnl.0b013e31827f07ab